Selected Published Scientific Articles

The following abstracts to peer-reviewed published articles report some of the most advanced scientific and clinical research in the field of sperm DNA damage, antioxidants and male fertility. These abstracts are provided for free through the NIH government site, PubMed. However, you may have to pay if you wish to obtain the full article.

  1. A novel antioxidant formulation designed to treat male infertility associated with oxidative stress: promising preclinical evidence from animal models.  Gharagozloo P, Aitken RJ, et al. Human Reproduction. 2016 Feb;31(2): 252-262. http://www.ncbi.nlm.nih.gov/pubmed/26732620 
  2. The role of sperm oxidative stress in male fertility and the significance of oral antioxidant therapy. Gharagozloo P, Aitken RJ., Human Reproduction. 2011 Jul;26(7):1628-40. http://www.ncbi.nlm.nih.gov/pubmed/21546386
  3. Antioxidants for male subfertility. Showell MG, Brown J, Yazdani A, Stankiewicz MT, Hart RJ.Cochrane Database Systematic Review. 2011 Jan 19;(1):CD007411. http://www.ncbi.nlm.nih.gov/pubmed/21249690
  4. Correlation between DNA damage and sperm parameters: a prospective study of 1,633 patients. Cohen-Bacrie P, Belloc S, Ménézo YJ, Clement P, Hamidi J, Benkhalifa M. Fertil Steril. 2009 May;91(5):1801-5. http://www.ncbi.nlm.nih.gov/pubmed/18439595
  5. Role of increased male age in IVF and egg donation: is sperm DNA fragmentation responsible? Humm KC, Sakkas D., Fertil Steril. 2013 Jan;99(1):30-6. http://www.ncbi.nlm.nih.gov/pubmed/23273987
  6. Sperm DNA damage has a negative association with live-birth rates after IVF. Simon L, Proutski I, Stevenson M, Jennings D, McManus J, Lutton D, Lewis SE., Reprod Biomed Online. 2013 Jan;26(1):68-78. http://www.ncbi.nlm.nih.gov/pubmed/23200202
  7. Sperm chromatin structure assay (SCSA®). Evenson DP., Methods Mol Biol. 2013;927:147-64. http://www.ncbi.nlm.nih.gov/pubmed/22992911
  8. Reactive oxygen species and sperm function--in sickness and in health. Aitken RJ, Jones KT, Robertson SA., J Androl. 2012 Nov-Dec;33(6):1096-106. http://www.ncbi.nlm.nih.gov/pubmed/22879525
  9. Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria. Aitken RJ, De Iuliis GN, Finnie JM, Hedges A, McLachlan RI., Hum Reprod. 2010 Oct;25(10):2415-26. http://www.ncbi.nlm.nih.gov/pubmed/20716559
  10. Importance of father's age to disease risk.Kong A, Frigge ML, Masson G, Besenbacher S, Sulem P, Magnusson G, Gudjonsson SA, Sigurdsson A, Jonasdottir A, Jonasdottir A, Wong WS, Sigurdsson G, Walters GB, Steinberg S, Helgason H, Thorleifsson G, Gudbjartsson DF, Helgason A, Magnusson OT, Thorsteinsdottir U, Stefansson K. Nature. 2012 Aug 23;488(7412):471-5. http://www.ncbi.nlm.nih.gov/pubmed/22914163
  11. O'Roak BJ, Vives L, Girirajan S, Karakoc E, Krumm N, Coe BP, Levy R, Ko A, Lee C, Smith JD, Turner EH, Stanaway IB, Vernot B, Malig M, Baker C, Reilly B, Akey JM, Borenstein E, Rieder MJ, Nickerson DA, Bernier R, Shendure J, Eichler EE. Nature. 2012 Apr 4;485(7397):246-50. http://www.ncbi.nlm.nih.gov/pubmed/22495309

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Sperm DNA Damage

Diagnosis of Sperm DNA Damage

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